|Substrate:||Substrate: Primate Cerebellum; Rodent Intestine/Liver|
|Reference Range:||Negative: <1:10|
|Note:||Note: Positive IFA samples are confirmed by Western Blot at an additional charge|
|CPT Code:||CPT Code: 86255|
|Schedule / Turnaround Time:||Schedule/Turnaround Time: Assay performed daily Monday-Friday. Report availability is within 48 hours from the time of specimen receipt.|
Specimen need not be refrigerated or frozen. Collect 2-3 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into white tube provided with Immco Diagnostics’ collection kits. If separation facilities are not available, the blood can be sent in the tube used for collection.
Sample Stability: Sample is stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8˚C) up to five days and frozen (-20˚C or lower) up to one year.
Clinical Relevance: Antibodies to Hu antigen are present in patients with paraneoplastic neurologic syndrome such as encephalomyelitis and are frequently associated with small cell lung cancer and neuroblastoma. Hu antibodies are rarely associated with non-small cell lung cancer, prostate cancer or seminoma.