Immunofluorescence IgG, IgA, IgM, Fibrin, C3 (C5b-9, IgG4)

Category: Dermatopathology & Ocular Pathology
Test Code: 510
Disease: Cutaneous Pathology/ autoimmune diseases
Methodology: Direct Immunofluorescence.
Reference Range: Not applicable. Detailed interpretation accompanies report.
Note: If a connective tissue disease is suspected, a test for the presence of C5b9 will be added at an additional charge. If a vesiculo-bullous disease (i.e. MMP, BP, PV, LABD, and EBA) is suspected, a test for the presence of IgG4 will be added at an additional charge.
CPT Code: 88346(x5, x6 or x7)
Schedule / Turnaround Time: Report availability is within 48 hours from the time of specimen receipt.
Specimen Requirements:

The red and purple tubes provided with Immco collection kits contain a holding solution for immunofluorescence specimens. A biopsy from a Lesional or Perilesional site should be placed in the red tube and a biopsy from a normal site should be placed in the purple tube. If these tubes are unavailable, submit specimen in Zeus/Michel’s fixative. Transport at room temperature.

Sample Stability:

Stable in appropriate solution at room temperature indefinitely.

Routine Panel tests for the Presence of: IgG; IgA; IgM; Fibrin; C3, C5b-9, and IgG4)
Biopsy Site Selection: Proper biopsy sites are dependent on the suspected diagnosis. See the preceeding table.