Yo antibody

Category: Neuroimmunology
Test Code: 501
Disease: Paraneoplastic Syndromes
Methodology: Indirect Immunofluorescence
Substrate: Substrate: Primate Cerebellum; Rodent Intestine/Liver
Reference Range: Negative: <1:10
Units: Units: Titer
Note: *Note: Positive IFA samples are confirmed by Western Blot for an additional charge
CPT Code: CPT Code: 86255
Schedule / Turnaround Time: Schedule/Turnaround Time: Assay performed daily Monday-Friday. Report availability is within 48 hours from the time of specimen receipt.
Specimen Requirements:

Specimen need not be refrigerated or frozen. Collect 2-3 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into white tube provided with Immco Diagnostics’ collection kits. If separation facilities are not available, the blood can be sent in the tube used for collection.

Sample Stability:

Sample Stability: Sample is stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8˚C) up to five days and frozen (-20˚C or lower) up to one year.


Clinical Relevance: Antibodies to Yo are associated with paraneoplastic disorders (cerebellar degeneration) as well as with small cell lung cancer, gynecologic and breast cancer.