Infection with mumps virus, whether symptomatic or subclinical, is generally thought to offer lifelong immunity. Anti-Mumps virus IgM appear 2- 3 days after the occurrence of the first clinical symptoms (and remain 2-3 months), followed by the production of Mumps IgG antibodies which persist lifelong.

Following vaccination with live virus there is a seroconversion in 90% of cases, however, the titre is somewhat lower than in normal infections.

EIA is as sensitive as the neutralization test and more sensitive than CF and HAI which makes it a reliable test for determination of immune status.

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